A new publication from our lab with Ki-Jo, Minseung, Iannis and Prof. Tagkopoulos on curating a Rheumatoid arthritis (RA) synovial genome-scale transcriptomic profiles which cover an intersection of 11769 genes from 11 datasets. Three clusters with different pathway signatures are observed and the prediction model using gene expression level as input for drug effectiveness are built.
Kim, K. J., Kim, M., Adamopoulos, I., & Tagkopoulos, I. (2019). Compendium of synovial signatures identifies pathologic characteristics for predicting treatment response in rheumatoid arthritis patients. Clinical Immunology.